People: Varsha, Praveen, Mari, Agata, Karen, Thomas, Santiago
- Thomas: Mimic an Artificial immune system using DNA origami boxes and a signal amplification. Bring up an example with the boxes using in cancer research. Create a DNA Transformer: Complex reformation of a shape on a nanoscale
- Agata: Use motor proteins to sort things. Problem with dimensions of DNA Origami and Microtubules/Motor Technology.In Schäffers group they investigate the fighting of Motor proteins, some go to the + end some to the – end. They use DNA Origami to connect the motors. Create caps and it can not further grow. Is it possible to add the Biotin to the ends. Coat surface with gold. Bending abilities? How efficient is the microtubule system? Create a cap and connect the cap and therefore create a path for the Motors.
- Praveen: DNA Origami coupled with microtubule/kinesin system – biosensor. Distance movement is coupled to the amount of molecules you have. This is a very sensitive single molecule sensor. Correlation between amount of ATP you have and irregular movement. DNA Nanorockets coupled with DNA Origami and Smart Polymers: Drop boxes to a specific site.
- Karen: An artificial signaling cascade using DNA origami coupled to a membrane. Two Origamis on a membrane sheet. Brought together by an Aptamer clamp and the complementary strand would bind together to be able to form a double strand and do an artificial transcription system.
- Santiago: DNA piston Tetrahedron with Hairpin structure. Fuel with a hairpin and a handle at the end. Elongation of the structure -> creation of a spring (elongated-stretched-…). Fuel-Antifuel system. Idea use three tetrahedron together to form a large extension.
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